DOT1L

Reference Set (30 Compounds)

CC(C)N(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 ZINC000166456976

ZINC000166456976 (search)

CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(Cl)c(C(F)(F)F)cc3[nH]2)C1 ZINC000167949263

ZINC000167949263 (search)

CN(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 ZINC000166457109

ZINC000166457109 (search)

CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 ZINC000100074350

ZINC000100074350 (search)

CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 ZINC000168212088

ZINC000168212088 (search)

CC(C)N(C[C@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(OC(F)(F)F)ccc3[nH]2)C1 ZINC000168379400

ZINC000168379400 (search)

CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@@H](CCc2nc3ccc(OC(F)(F)F)cc3[nH]2)C1 ZINC001772583489

ZINC001772583489 (search)

CN(C[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@H]1C[C@H](CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1 ZINC000168011047

ZINC000168011047 (search)

CC(C)N(CCCNC(=O)Nc1nc2ccc(C(C)(C)C)cc2[nH]1)C[C@@H]1O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O ZINC000169702057

ZINC000169702057 (search)

CC(C)(C)c1ccc(NC(=O)NCCCNC[C@@H]2O[C@H](n3ccc4c(N)ncnc43)[C@@H](O)[C@H]2O)cc1 ZINC000169702059

ZINC000169702059 (search)

CC(=O)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@@H]1O[C@H](n2ccc3c(N)ncnc32)[C@@H](O)[C@H]1O ZINC000169702060

ZINC000169702060 (search)

CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O ZINC000103293048

ZINC000103293048 (search)

CC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)CC1=C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O ZINC000103293046

ZINC000103293046 (search)

O=C(CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)NCCCCN[C@@H]1CCCN(c2ncnc3[nH]ccc23)C1 ZINC001772578353

ZINC001772578353 (search)

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CN(CCI)CCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O ZINC000103295987

ZINC000103295987 (search)

CC(C)(C)c1ccc(NC(=O)NCCCSC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1 ZINC000103293051

ZINC000103293051 (search)

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O ZINC000004228232

ZINC000004228232 (search)

CNc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O ZINC000013522181

ZINC000013522181 (search)

N[C@@H](CCSC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O)C(=O)O ZINC000038576043

ZINC000038576043 (search)

C[C@@H]([C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)N(C1CCC1)C1CC(CCc2nc3ccc(C(C)(C)C)cc3[nH]2)C1 ZINC001772601180

ZINC001772601180 (search)

C[C@@H]([C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)N(C1CC(CCc2nc3ccc(C(C)(C)C)cc3[nH]2)C1)C1CC(CCc2nc3ccc(C(C)(C)C)cc3[nH]2)C1 ZINC001772583446

ZINC001772583446 (search)

CCCCNc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O ZINC000038281040

ZINC000038281040 (search)

c1ccc2c(c1)nnn2Cc1nnc2sc(-c3ccc4c(c3)OCO4)nn12 ZINC000004867942

ZINC000004867942 (search)

Brc1cccc(-c2nn3c(Cn4cnc5ccccc54)nnc3s2)c1 ZINC000001016496

ZINC000001016496 (search)

CC(C)(C)c1ccc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)cc1 ZINC000005322272

ZINC000005322272 (search)

Fc1ccc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)cc1 ZINC000002365829

ZINC000002365829 (search)

COc1cccc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 ZINC000002360119

ZINC000002360119 (search)

CC(C)(C)Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O ZINC000036418584

ZINC000036418584 (search)

Fc1cccc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 ZINC000002433975

ZINC000002433975 (search)

c1ccc2c(c1)nnn2Cc1nnc2sc(-c3ccc4c(c3)OCCO4)nn12 ZINC000002879384

ZINC000002879384 (search)