ORAI1

Reference Set (105 Compounds)

O=C(Cn1nnc2ccccc21)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 ZINC000116816212

ZINC000116816212 (search)

O=C(Cn1nnc2ccccc21)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 ZINC000117439194

ZINC000117439194 (search)

O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1)c1ccc2nccnc2c1 ZINC000116815134

ZINC000116815134 (search)

O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1)c1ccc2ncccc2c1 ZINC000116815159

ZINC000116815159 (search)

O=C(Cn1nc2ccccc2n1)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 ZINC000116816753

ZINC000116816753 (search)

O=C(Cc1ccc2ncccc2c1)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 ZINC000116815113

ZINC000116815113 (search)

O=C(Cn1nnc2ccccc21)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1 ZINC000117448110

ZINC000117448110 (search)

O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1ccc2nn[nH]c2c1 ZINC000117456684

ZINC000117456684 (search)

O=C(Cc1ccc2ncccc2c1)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)c(F)c1 ZINC000116814738

ZINC000116814738 (search)

O=C(Cn1cnc2ccccc21)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 ZINC000117438325

ZINC000117438325 (search)

Fc1cc(F)c(CNc2ccc(Oc3ccccc3C(F)(F)F)cn2)c(F)c1 ZINC000144041657

ZINC000144041657 (search)

Cc1cc2c(cc1-c1ccc(NCc3c(F)cccc3F)nc1)OCCO2 ZINC000149798726

ZINC000149798726 (search)

Cc1cccc(F)c1CNc1ccc(-c2cc(C(F)(F)F)nn2C)cn1 ZINC000149804553

ZINC000149804553 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NCc2ccccc2F)nc1 ZINC000149805823

ZINC000149805823 (search)

Cc1cc(Cl)ncc1-c1cnc(NCc2c(F)cc(Cl)cc2F)nc1 ZINC000149806639

ZINC000149806639 (search)

Cc1nc(C(F)(F)F)cn1-c1ccc(NCc2c(F)cc(F)cc2F)nc1 ZINC000149806861

ZINC000149806861 (search)

COc1cc(C)c(-c2cnc(NCc3c(F)cccc3F)nc2)cn1 ZINC000149807756

ZINC000149807756 (search)

Cc1cc(C(F)(F)F)nn1-c1ccc(NCc2c(F)cc(F)cc2F)nc1 ZINC000149807968

ZINC000149807968 (search)

COc1cc(F)c(CNc2ncc(-c3cc4c(cc3C)OC(F)(F)O4)cn2)c(F)c1 ZINC000149808416

ZINC000149808416 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cncc2F)nc1 ZINC000149809561

ZINC000149809561 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)ccc(F)c2F)nc1 ZINC000149809785

ZINC000149809785 (search)

Cc1cc2c(cc1-c1ccc(NCc3c(F)cccc3F)nc1)OC(F)(F)O2 ZINC000149810203

ZINC000149810203 (search)

Fc1cccc(F)c1CNc1ccc(-c2cc3c(cc2Cl)OC(F)(F)O3)cn1 ZINC000149811070

ZINC000149811070 (search)

Fc1cc(F)c(CNc2ccc(-n3nc(C(F)(F)F)cc3C(F)(F)F)cn2)c(F)c1 ZINC000149811759

ZINC000149811759 (search)

Fc1cccc(F)c1CNc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cn1 ZINC000149813841

ZINC000149813841 (search)

COc1cc(F)c(CNc2ccc(-n3nc(C(F)(F)F)cc3C)cn2)c(F)c1 ZINC000149815339

ZINC000149815339 (search)

Cc1cc(C(F)(F)F)nn1-c1ccc(NCc2c(F)cccc2F)nc1 ZINC000149818117

ZINC000149818117 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2ccc(F)cc2F)nc1 ZINC000149819005

ZINC000149819005 (search)

Fc1cccc(F)c1CNc1ncc(Oc2ccccc2C(F)(F)F)cn1 ZINC000149824672

ZINC000149824672 (search)

Cc1cc(C(F)(F)F)nn1-c1ccc(NCc2c(F)cncc2F)nc1 ZINC000149826164

ZINC000149826164 (search)

Cc1nc(C(F)(F)F)cn1-c1ccc(NCc2c(F)cccc2F)nc1 ZINC000149843522

ZINC000149843522 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cc(F)cc2F)nc1 ZINC000150274625

ZINC000150274625 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2ccccc2F)nc1 ZINC000207714649

ZINC000207714649 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cccc2F)nc1 ZINC000207714902

ZINC000207714902 (search)

Cc1cc2c(cc1-c1ccc(NCc3c(F)cccc3F)nc1)CCC2 ZINC000207719579

ZINC000207719579 (search)

Fc1cccc(CNc2ccc(-c3cc4c(cc3Cl)OC(F)(F)O4)cn2)c1 ZINC000207720495

ZINC000207720495 (search)

Cc1ccccc1CNc1ccc(-c2cc3c(cc2C)OC(F)(F)O3)cn1 ZINC000207720619

ZINC000207720619 (search)

Cc1cc2c(cc1-c1ccc(NCc3ccccc3F)nc1)OC(F)(F)O2 ZINC000207720743

ZINC000207720743 (search)

Cc1cc2c(cc1-c1cnc(NCc3c(F)cc(F)cc3F)cn1)OC(F)(F)O2 ZINC000207720921

ZINC000207720921 (search)

Cc1cc(F)ccc1CNc1ccc(-c2nc3c(cc2Cl)OCCO3)cn1 ZINC000207721304

ZINC000207721304 (search)

Fc1cccc(F)c1CNc1ccc(Oc2ccccc2C(F)(F)F)cn1 ZINC000207723914

ZINC000207723914 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2ccccc2F)nc1N ZINC000207724161

ZINC000207724161 (search)

Cc1cc2scnc2cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000114453669

ZINC000114453669 (search)

Cc1cc2scnc2cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000114454349

ZINC000114454349 (search)

Cc1cc2scnc2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000114454359

ZINC000114454359 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000114454900

ZINC000114454900 (search)

O=C(Nc1ccccc1Cl)c1ccc(-c2cc3scnc3cc2Cl)s1 ZINC000114455315

ZINC000114455315 (search)

O=C(Nc1c(F)cccc1F)c1ccc(-c2cc3scnc3cc2Cl)s1 ZINC000114456020

ZINC000114456020 (search)

Cc1nc(-c2cc(-c3ccc(C(=O)Nc4ccccc4F)s3)n(C)n2)no1 ZINC000114457060

ZINC000114457060 (search)

Cc1nc(-c2cc(-c3ccc(C(=O)Nc4c(F)cccc4F)s3)n(C)n2)no1 ZINC000114457449

ZINC000114457449 (search)

Cc1nc2cc(Cl)c(-c3cnc(NC(=O)c4ccccc4Cl)s3)cc2o1 ZINC000114457548

ZINC000114457548 (search)

Cc1cc2c(C)noc2cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000114460984

ZINC000114460984 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccccc2F)s1 ZINC000142565844

ZINC000142565844 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2c(F)cccc2F)s1 ZINC000142566068

ZINC000142566068 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccccc2Cl)s1 ZINC000142566518

ZINC000142566518 (search)

CCn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccccc2Cl)s1 ZINC000142568664

ZINC000142568664 (search)

Cn1nc(-c2ccccc2F)cc1-c1cnc(NC(=O)c2ccccc2F)s1 ZINC000142571145

ZINC000142571145 (search)

Cn1nc(-c2ccccc2)cc1-c1cnc(NC(=O)c2ccccc2F)s1 ZINC000142572065

ZINC000142572065 (search)

Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3F)s1)OC(F)(F)O2 ZINC000142576096

ZINC000142576096 (search)

Cc1cc2scnc2cc1-c1cnc(NC(=O)c2c(F)cccc2F)s1 ZINC000142577001

ZINC000142577001 (search)

O=C(Nc1ccccc1F)c1ccc(-c2cc3scnc3cc2Cl)s1 ZINC000142579371

ZINC000142579371 (search)

Cc1cc2c(C)noc2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142579605

ZINC000142579605 (search)

Cc1cc2cn(C)nc2cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000142580048

ZINC000142580048 (search)

Cc1cc2cn(C)nc2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142580288

ZINC000142580288 (search)

Cc1cc2cn(C)nc2cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000142580502

ZINC000142580502 (search)

Cc1cc2cnn(C)c2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142580731

ZINC000142580731 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000142581649

ZINC000142581649 (search)

Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4ccccc4F)s3)cc2o1 ZINC000142582925

ZINC000142582925 (search)

Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4ccccc4Cl)s3)cc2o1 ZINC000142583155

ZINC000142583155 (search)

Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4c(F)cccc4F)s3)cc2o1 ZINC000142583371

ZINC000142583371 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000142584904

ZINC000142584904 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 ZINC000142585108

ZINC000142585108 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 ZINC000142587490

ZINC000142587490 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 ZINC000142588151

ZINC000142588151 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142591006

ZINC000142591006 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142592183

ZINC000142592183 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000142593081

ZINC000142593081 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 ZINC000142593940

ZINC000142593940 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000142594360

ZINC000142594360 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ccccc2F)s1 ZINC000142595670

ZINC000142595670 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000142596114

ZINC000142596114 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 ZINC000142596802

ZINC000142596802 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ccccc2Cl)s1 ZINC000142598334

ZINC000142598334 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2F)s1 ZINC000142611240

ZINC000142611240 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)s1 ZINC000142611469

ZINC000142611469 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 ZINC000142660915

ZINC000142660915 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 ZINC000142661127

ZINC000142661127 (search)

Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ccncc2F)s1 ZINC000142661334

ZINC000142661334 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 ZINC000142662437

ZINC000142662437 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ccncc2F)s1 ZINC000142662917

ZINC000142662917 (search)

Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 ZINC000142663136

ZINC000142663136 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2ccncc2F)s1 ZINC000142665703

ZINC000142665703 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 ZINC000142665925

ZINC000142665925 (search)

Cn1nc(-c2nccs2)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 ZINC000142666572

ZINC000142666572 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 ZINC000142668743

ZINC000142668743 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2ccncc2F)s1 ZINC000142669398

ZINC000142669398 (search)

Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 ZINC000142669632

ZINC000142669632 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccc(Cl)cc2)s1 ZINC000142675203

ZINC000142675203 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccncc2F)s1 ZINC000142676458

ZINC000142676458 (search)

Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2c(F)cncc2F)s1 ZINC000142677147

ZINC000142677147 (search)

Cc1cc2c(cc1-c1cnc(NC(=O)c3ccncc3F)s1)OC(F)(F)O2 ZINC000142681650

ZINC000142681650 (search)

Cn1nc(C(F)(F)F)cc1-c1cnc2[nH]c(-c3c(F)cccc3Cl)cc2c1 ZINC000206923833

ZINC000206923833 (search)

COc1cc(C)c(-c2cnc3[nH]c(-c4c(F)cccc4Cl)cc3c2)cn1 ZINC000213597294

ZINC000213597294 (search)

COc1cc(OC)c(-c2cnc3[nH]c(-c4c(F)cccc4Cl)cc3c2)cn1 ZINC000222868257

ZINC000222868257 (search)

Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 ZINC000000591398

ZINC000000591398 (search)